Title of article
General synthesis of (1-substituted-1H-1,2,3-triazol-4-ylmethyl)-dialkylamines via a copper(I)-catalyzed three-component reaction in water
Author/Authors
Ze yi Yan، نويسنده , , Ya-Bin Zhao، نويسنده , , Mingjin Fan، نويسنده , , Weimin Liu، نويسنده , , Yong-Min Liang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
7
From page
9331
To page
9337
Abstract
A copper(I)-catalyzed three-component reaction to form (1-substituted-1H-1,2,3-triazol-4-ylmethyl)-dialkylamines based on the Huisgen cycloaddition using amine, propargyl halide and azide in water was proposed. The process showed considerable synthetic advantages in terms of high atom economy, low environmental impact, atmospheric oxygen, wide substrate scope, mild reaction condition and good yields.
Keywords
Water , Huisgen cycloaddition , Copper(I)-catalyzed , Three-component reaction
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1089161
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