Title of article
Total synthesis of lamellarins D, L, and N
Author/Authors
Naotaka Fujikawa، نويسنده , , Takeshi Ohta، نويسنده , , Tomohiro Yamaguchi، نويسنده , , Tsutomu Fukuda، نويسنده , , Fumito Ishibashi، نويسنده , , Masatomo Iwao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
11
From page
594
To page
604
Abstract
Total synthesis of cytotoxic marine alkaloids, lamellarins D, L, and N, has been achieved by using Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki–Miyaura coupling of the 3,4-dihydroxypyrrole bistriflate as the key reactions. The total yields of lamellarins D, L, and N from the common intermediate are 54, 58, and 50%, respectively.
Keywords
Total synthesis , Lamellarin , Hinsberg reaction , Suzuki–Miyaura coupling
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089523
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