Title of article
Synthesis of dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones bearing a sugar moiety
Author/Authors
Hélène Hénon، نويسنده , , Fabrice Anizon، نويسنده , , Bruno Pfeiffer، نويسنده , , Michelle Prudhomme، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
8
From page
1116
To page
1123
Abstract
The synthesis of a series of dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, structurally related to the G2 checkpoint inhibitor granulatimide and bearing a sugar moiety, is described. Substitutions were carried out at the 6-position of the glycosyl unit to lead to an amino substituent as observed in many biologically active compounds such as anthracyclins or staurosporines.
Keywords
6-tetraone , Granulatimide , Antitumor agents , 4-a:3 , 4-c]carbazole-1 , 3 , 4
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089579
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