Title of article
Synthesis of a chiral steroid ring D precursor starting from carvone
Author/Authors
Serghei Pogrebnoi، نويسنده , , Florence C.E Sarabèr، نويسنده , , Ben J.M Jansen، نويسنده , , Aede de Groot، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
6
From page
1743
To page
1748
Abstract
A chiral five-membered, silyl enol ether containing, steroid ring D precursor has been synthesized from carvone. This silyl enol ether has been applied in the synthesis of a chiral C17 functionalized steroid skeleton using the addition of a carbocation, generated with ZnBr2 from a Torgov reagent, followed by cyclization of the adduct by treatment with acid.
Keywords
Mukaiyama–Michael addition , carvone , Chiral silyl enol ethers , D-trans steroid synthesis , C
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089647
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