Title of article
Asymmetric alkylation of diarylmethane derivatives
Author/Authors
James A. Wilkinson، نويسنده , , Steven B. Rossington، نويسنده , , Sylvie Ducki، نويسنده , , John Leonard، نويسنده , , Nigel Hussain، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
12
From page
1833
To page
1844
Abstract
Deprotonation–alkylation of prochiral diarylmethane substrates using sec-BuLi and (−)-sparteine has been carried out in excellent yields and up to 94% ee. A variety of enantioselective alkylations, silylations and stannylations have been performed on four different diarylmethanes. Surrogates for (+)-sparteine have also been applied in this study including a novel surrogate.
Keywords
Alkylation , sparteine , Asymmetric , Diarylmethane
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089659
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