• Title of article

    Stereoselective synthesis of Sch 642305, an inhibitor of bacterial DNA primase

  • Author/Authors

    Ken Ishigami، نويسنده , , Ryo Katsuta، نويسنده , , Hidenori Watanabe، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    7
  • From page
    2224
  • To page
    2230
  • Abstract
    Sch 642305 is a fungal nonanolide, which inhibits bacterial DNA primase and HIV-1 Tat transactivation. The enantioselective synthesis of Sch 642305 was succeeded starting from useful chiral building block via stereoselective dianion alkylation of β-ketosulfoxide and lactonization.
  • Keywords
    Sch 642305 , DNA primase , Lactonization
  • Journal title
    Tetrahedron
  • Serial Year
    2006
  • Journal title
    Tetrahedron
  • Record number

    1089700