Title of article
Stereoselective synthesis of Sch 642305, an inhibitor of bacterial DNA primase
Author/Authors
Ken Ishigami، نويسنده , , Ryo Katsuta، نويسنده , , Hidenori Watanabe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
7
From page
2224
To page
2230
Abstract
Sch 642305 is a fungal nonanolide, which inhibits bacterial DNA primase and HIV-1 Tat transactivation. The enantioselective synthesis of Sch 642305 was succeeded starting from useful chiral building block via stereoselective dianion alkylation of β-ketosulfoxide and lactonization.
Keywords
Sch 642305 , DNA primase , Lactonization
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089700
Link To Document