Palladium-catalyzed cross-coupling reaction of alkenyl bromides with potassium alkyltrifluoroborates

The Suzuki–Miyaura-type cross-coupling reaction of potassium alkyltrifluoroborates with various alkenyl bromides in the presence of 10 mol % of PdCl2(dppf)·CH2Cl2 and 3.0 equiv of Cs2CO3 in aqueous toluene at 80 °C provided the desired compounds in 63–95% yields. A variety of functional groups in the potassium alkyltrifluoroborates were tolerated under the basic conditions.