Title of article
Convenient synthesis of fluorinated quinoline, 1,2-dihydroquinoline, and 1,2,3,4-tetrahydroquinoline derivatives
Author/Authors
Hikaru Yanai، نويسنده , , Hideyuki Mimura، نويسنده , , Kosuke Kawada، نويسنده , , Takeo Taguchi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
8
From page
2153
To page
2160
Abstract
A convenient synthetic method for 2-polyfluoroalkylated quinoline systems through the efficient generation of perfluoroalkylated imine from o-vinylanilines with perfluorinated hemiacetals or aldehyde hydrates was developed. In most cases, the major products are 2-polyfluoroalkyl-1,2-dihydroquinoline derivatives 3, which can be converted to either quinolines or 1,2,3,4-tetrahydroquinolines.
Keywords
Fluorinated heterocycles , Quinoline , 2-dihydroquinoline , 1 , Trifluoroacetaldehyde ethyl hemiacetal
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090360
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