Title of article
Stereoselective synthesis of β-amino ketones via direct Mannich-type reaction catalyzed with silica sulfuric acid
Author/Authors
Hui Wu، نويسنده , , Chen-Yang Shen، نويسنده , , Li-yan Fan، نويسنده , , Yu Wan، نويسنده , , Pu Zhang، نويسنده , , Cai-fa Chen، نويسنده , , Wenxiang Wang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
2404
To page
2408
Abstract
At room temperature, the direct Mannich-type reaction of a variety of in situ generated aldimines using aldehydes and anilines with ketones in a three-component reaction was efficiently catalyzed by silica sulfuric acid (SSA) in EtOH. This rapid reaction afforded the corresponding β-amino ketones in good yields with excellent stereoselectivities and catalyst was recyclable.
Keywords
?-Amino ketones , Synthesis , silica sulfuric acid , Direct Mannich-type reaction
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090408
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