Title of article
Comparison of enantioselective reductions using bead and monolith ‘disk’ polymer formulations of CBS catalysts
Author/Authors
Michael C. Varela، نويسنده , , Seth M. Dixon، نويسنده , , Michael D. Price، نويسنده , , Jeffrey E. Merit، نويسنده , , Patrick E. Berget، نويسنده , , Saori Shiraki، نويسنده , , Mark J. Kurth، نويسنده , , Neil E. Schore، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
6
From page
3334
To page
3339
Abstract
Two polymer-supported versions of the Corey, Bakshi, and Shibata (CBS) catalyst were prepared and examined. Polymeric beads, with the auxiliary bound in pendant and crosslinked fashion, were prepared utilizing an improved procedure based upon earlier work. Optimization of a procedure for ketone reduction gives results that match those in solution. Attempted reuse gave mixed results. For comparison purposes, CBS functionalized monoliths were formed and tested but performed poorly.
Keywords
Crosslinking monomer , Polymer beads , CBS catalyst , enantioselective reduction , Polymer disks
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090574
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