Title of article
Solid-phase carbohydrate synthesis via on-bead protecting group chemistry
Author/Authors
Hilbert M. Branderhorst، نويسنده , , Rob M.J. Liskamp، نويسنده , , Roland J. Pieters، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
7
From page
4290
To page
4296
Abstract
Di- and tri-saccharides were synthesized on a solid phase. The procedure started with a non-protected sugar linked via either cysteine or glutamine to a polystyrene resin. Selective dimethoxytritylation chemistry and subsequent steps yielded a resin-bound acceptor that could be glycosylated to yield β1,6-linked disaccharides. Reiteration of the procedure produced the trisaccharide.
Keywords
Glycosylation , Solid-phase synthesis , Carbohydrates
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090744
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