Synthesis of polyarene derivatives of fused aziridines by Suzuki–Miyaura cross-coupling

A convenient and effective synthetic approach to potentially radiochromic polyarene derivatives of bi- and tricyclic aziridines utilizing modified Suzuki–Miyaura cross-coupling with catalysis in micellar media has been developed. A series of polyarene substituents were introduced into 1,5-diaryl-3,5a-dihydro-1H-azireno[1,2-c]imidazoles, 1,6-diaryl-1,3,4,6a-tetrahydroazireno[1,2-a]pyrazines, and 1,2-diaryl-1,1a-dihydroazireno[1,2-a]quinoxalines without degradation of the highly reactive aziridine ring system.