Title of article
Three-component coupling using arynes and isocyanides: straightforward access to benzo-annulated nitrogen or oxygen heterocycles
Author/Authors
Hiroto Yoshida، نويسنده , , Hiroyuki Fukushima، نويسنده , , Takami Morishita، نويسنده , , Joji Ohshita، نويسنده , , Atsutaka Kunai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
13
From page
4793
To page
4805
Abstract
A variety of aldehydes, ketones, benzoquinones, or sulfonylimines were found to couple with arynes and isocyanides, giving iminodihydroisobenzofuran or iminoisoindoline derivatives of structural diversity in a straightforward manner. Nucleophilic addition of isocyanides to arynes, a first step of the three-component coupling, was proved to be reversible by the reaction of an unsymmetrical aryne.
Keywords
Oxygen heterocycle , Three-component coupling , nitrogen heterocycle , isocyanide , aryne
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090845
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