Title of article
CuI–Fesulphos complexes: efficient chiral catalysts for asymmetric 1,3-dipolar cycloaddition of azomethine ylides
Author/Authors
Silvia Cabrera، نويسنده , , Ram?n G?mez Array?s، نويسنده , , Belén Mart?n-Matute، نويسنده , , Fernando P. Coss?o، نويسنده , , Juan C. Carretero، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
16
From page
6587
To page
6602
Abstract
The CuI–Fesulphos catalyst system (≤3 mol %) shows an excellent performance in the asymmetric 1,3-dipolar cycloaddition of azomethine ylides. High to very high levels of reactivity, endo/exo selectivity, and enantioselectivity (69–>99% ee) are generally achieved with a very wide range of azomethine ylides and dipolarophiles. Based on experimental and computational studies data, a model that accounts for this high enantiocontrol is proposed.
Keywords
1 , chiral ligand , Asymmetric catalysis , copper , Enantioselectivity , 3-dipolar cycloaddition , azomethine ylide , Dipolarophile
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1091151
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