Title of article
Cobalt-catalyzed sequential cyclization/cross-coupling reactions of 6-halo-1-hexene derivatives with Grignard reagents and their application to the synthesis of 1,3-diols
Author/Authors
Hidenori Someya، نويسنده , , Hirohisa Ohmiya، نويسنده , , Hideki Yorimitsu، نويسنده , , Koichiro Oshima، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
10
From page
8609
To page
8618
Abstract
Cobalt/N-heterocyclic carbene system or cobalt/diamine combination effectively catalyzes sequential cyclization/cross-coupling reactions of 6-halo-1-hexene derivatives with trialkylsilylmethyl, 1-alkynyl, and aryl Grignard reagents. The sequential cyclization/cross-coupling reactions are applied to the synthesis of 1,3-diols starting from siloxy-tethered 6-halo-1-hexene derivatives.
Keywords
Cobalt , cross-coupling reaction , 3-Diols , Grignard reagent , 1 , N-heterocyclic carbene
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1091559
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