Title of article
AIBN-initiated radical addition of gem-difluorinated alkyl iodides to alkynes and the Pd-catalyzed Sonogashira coupling reaction of E-phenyl difluoromethylene vinylic iodides with terminal alkynes
Author/Authors
Xiang Fang، نويسنده , , Xueyan Yang، نويسنده , , Xianjin Yang، نويسنده , , Shenjie Mao، نويسنده , , Zhonghua Wang، نويسنده , , Guorong Chen، نويسنده , , Fanhong Wu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
9
From page
10684
To page
10692
Abstract
The addition of gem-difluorinated alkyl iodides to alkynes initiated by AIBN neatly gave the corresponding difluoromethylene vinyl iodides among which the stereoselectivity of aromatic acetylenes was high. The further coupling reaction of E-phenyl difluoromethylene vinyl iodides with terminal alkynes in the presence of catalytic palladium afforded the substituted difluorinated enynes.
Keywords
alkynes , Difluoromethylene vinylic iodides , Sonogashira coupling , Radical addition
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1093336
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