• Title of article

    Synthesis of 2′-O-α-d-ribofuranosyladenosine, monomeric unit of poly(ADP–ribose)

  • Author/Authors

    Sergey N. Mikhailov، نويسنده , , Irina V. Kulikova، نويسنده , , Koen Nauwelaerts، نويسنده , , Piet Herdewijn، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    6
  • From page
    2871
  • To page
    2876
  • Abstract
    The first chemical synthesis of 2′-O-α-d-ribofuranosyladenosine, monomeric unit of poly(ADP–ribose), has been achieved starting from 3′,5′-O-bis protected 9-(2-O-α-d-arabinofuranosyl-β-d-ribofuranosyl)-adenine. Configurational inversion of 2′-hydroxyl group of arabinose moiety was performed by oxidation–reduction sequence.
  • Keywords
    Poly(ADP–ribose) , Stereoselective synthesis , Monomeric unit
  • Journal title
    Tetrahedron
  • Serial Year
    2008
  • Journal title
    Tetrahedron
  • Record number

    1093888