• Title of article

    New stabilising groups for lateral lithiation of ortho-cresol derivatives and a new route to 2-substituted chromans

  • Author/Authors

    James A. Wilkinson، نويسنده , , Eun-Ang Raiber، نويسنده , , Sylvie Ducki، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    5
  • From page
    6329
  • To page
    6333
  • Abstract
    2-(2-Methoxyethoxy)-toluene and 2-(2-dimethylaminoethoxy)-toluene have been lithiated using sec-BuLi under a variety of conditions and the laterally lithiated species trapped with electrophiles, including but-1-ene oxide, leading to a new synthesis of 2-ethylchroman.
  • Keywords
    lateral lithiation , Alkylation , ortho-cresol , chromans
  • Journal title
    Tetrahedron
  • Serial Year
    2008
  • Journal title
    Tetrahedron
  • Record number

    1094262