Title of article
Simultaneous 2-O-deacetylation and 4-amination of peracetylated Neu5Ac: application to the synthesis of (4→4)-piperazine derivatives linked sialic acid dimers
Author/Authors
Deju Ye، نويسنده , , Guanghui Deng، نويسنده , , Wenfeng Liu، نويسنده , , Yu Zhou، نويسنده , , Enguang Feng، نويسنده , , Hualiang Jiang and Helmut Grubmüller، نويسنده , , Hong Liu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
7
From page
6544
To page
6550
Abstract
A simultaneous stereoselective 2-O-deacetylation and 4-amination reaction of peracetylated Neu5Ac 1 has been established with cyclic secondary amines, such as 1-N-Boc-piperazine. Four C2-symmetric and two asymmetric sialic acid dimers with (4→4)-piperazine derivatives linked were synthesized. They may serve as precursors of unnatural polysialic acids.
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094291
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