Title of article
Neopentylphosphines as effective ligands in palladium-catalyzed cross-couplings of aryl bromides and chlorides
Author/Authors
Lensey L. Hill، نويسنده , , Joanna M. Smith، نويسنده , , William S. Brown، نويسنده , , Lucas R. Moore، نويسنده , , Paul Guevera، نويسنده , , Emily S. Pair، نويسنده , , Jake Porter، نويسنده , , Joe Chou، نويسنده , , Christopher J. Wolterman، نويسنده , , Raluca Craciun، نويسنده , , David A. Dixon، نويسنده , , Kevin H. Shaughnessy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
15
From page
6920
To page
6934
Abstract
The use of neopentylphosphine ligands in the palladium-catalyzed Suzuki, Sonogashira, Heck, and Hartwig–Buchwald couplings of aryl bromides and chlorides are reported. Di-tert-butylneopentylphosphine (DTBNpP) provided highly active catalysts for the coupling of aryl bromides at mild temperatures. Trineopentylphosphine, an air-stable trialkylphosphine, gave inactive catalysts at room temperature, but showed good activity in the H–B amination of aryl chlorides at elevated temperatures.
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094333
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