• Title of article

    Pt-catalyzed cyclization/migration of propargylic alcohols for the synthesis of 3(2H)-furanones, pyrrolones, indolizines, and indolizinones

  • Author/Authors

    Eric M. Bunnelle، نويسنده , , Cameron R. Smith، نويسنده , , Sharon K. Lee، نويسنده , , Surendra W. Singaram، نويسنده , , Allison J. Rhodes، نويسنده , , Richmond Sarpong، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    7
  • From page
    7008
  • To page
    7014
  • Abstract
    Several heterocycles such as furanones, pyrrolones, and indolizines, which are of pharmacological importance, are easily accessed via the Pt(II)-catalyzed heterocyclization/1,2-migration of propargylic ketols or hydroxy imine derivatives. This method sidesteps the challenges of traditional heteroaromatic oxygenation strategies such as regioselectivity and functional group tolerance in the syntheses of these heterocycles.
  • Journal title
    Tetrahedron
  • Serial Year
    2008
  • Journal title
    Tetrahedron
  • Record number

    1094343