Title of article
Synthesis of 1,3-bridged β-lactams embedded in a macrocyclic structure
Author/Authors
Miguel A. Sierra، نويسنده , , Mamen Rodr?guez-Fern?ndez، نويسنده , , Mar?a José Manche?o، نويسنده , , Luis Casarrubios، نويسنده , , Mar G?mez-Gallego، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
7
From page
9592
To page
9598
Abstract
A new approach to N1–C3 bridged macrocyclic β-lactams has been developed. Orthogonal functional groupsʹ protection combined with RCM has allowed the construction of the bicyclic systems bearing a β-lactam motif. These systems could represent a structural alternative to the actual lactamic antibiotics and may be further transformed into a broad variety of compounds.
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094649
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