Title of article
Free radical (phenylsulfonyl)difluoromethylation of alkynes with PhSO2CF2I reagent: stereoselective preparation of PhSO2CF2- and CF2H-substituted alkenes
Author/Authors
Ya Li، نويسنده , , Huaifeng Li، نويسنده , , Jinbo Hu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
478
To page
483
Abstract
Stereoselective free radical (phenylsulfonyl)difluoromethylation of terminal alkynes with iododifluoromethyl phenyl sulfone (PhSO2CF2I) has been accomplished by using Et3B/air as an initiator. The obtained PhSO2CF2-substituted vinyl iodides, which can be further subjected to Suzuki coupling and Sonogashira coupling reactions, are useful precursors for the preparation of many structurally diverse PhSO2CF2- and CF2H-substituted alkenes.
Keywords
Fluorine , Radical fluoroalkylation , (Phenylsulfonyl)difluoromethylation , Difluoromethyl
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1094991
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