Title of article
Tandem conjugate addition–aldol cyclization of 2-formylbenzylidenemalonate with ether radicals by the mediation of dimethylzinc
Author/Authors
Kenichi Yamada، نويسنده , , Masaru Maekawa، نويسنده , , Tito Akindele، نويسنده , , Yasutomo Yamamoto، نويسنده , , Mayu Nakano، نويسنده , , Kiyoshi Tomioka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
903
To page
908
Abstract
The chemoselective radical conjugate addition reaction of THF or 4,4,5,5-tetramethyl-1,3-dioxolane with 2-formylbenzylidenemalonate gave tandem conjugate addition–aldol cyclization product in one pot. The radical tandem reaction was extended to the asymmetric reaction using bis(8-phenylmenthyl) 2-formylbenzylidenemalonate as a chiral Michael acceptor to provide an enantioenriched indane derivative.
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095042
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