• Title of article

    Gold-catalyzed cycloisomerizations of ene-ynamides

  • Author/Authors

    Sylvain Couty، نويسنده , , Christophe Meyer، نويسنده , , Janine Cossy، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    24
  • From page
    1809
  • To page
    1832
  • Abstract
    The gold-catalyzed cycloisomerizations of 1,6-ene-ynamides proceed under mild conditions and lead to cyclobutanones from terminal or trimethylsilyl substituted ynamides, or to carbonyl compounds bearing a 2,3-methanopyrrolidine subunit from substrates possessing a propargylic alcohol moiety. High diastereoselectivities are observed with 1,6-ene-ynamides having a stereocenter at the α or β position of the nitrogen atom.
  • Journal title
    Tetrahedron
  • Serial Year
    2009
  • Journal title
    Tetrahedron
  • Record number

    1095152