Title of article
General and efficient synthetic approach to novel tricyclic spiroketones
Author/Authors
Guohua Chu، نويسنده , , Bertrand Le Bourdonnec، نويسنده , , Minghua Gu، نويسنده , , Christopher T. Saeui، نويسنده , , Roland E. Dolle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
7
From page
5161
To page
5167
Abstract
A general and efficient synthetic approach to tricyclic spiroketones of interest as useful scaffolds in drug discovery was developed. Starting from commercially available benzyl 4-oxo-1-piperidinecarboxylate (5), spirocyclic tetralone 4, spirocyclic indanone 14, and spirocyclic benzocycloheptanone 15 were synthesized via six reaction steps in excellent overall yield.
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1097141
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