• Title of article

    Asymmetric synthesis of (−)-tetrahydrolipstatin

  • Author/Authors

    Sadagopan Raghavan، نويسنده , , Kailash Rathore، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    10
  • From page
    10083
  • To page
    10092
  • Abstract
    Attempts toward the asymmetric synthesis of (−)-tetrahydrolipstatin are described. A palladium catalyzed Wacker-type reaction to convert an alkene to a ketone, highly diastereoselective reduction of a β-hydroxy ketone, selective oxidation of a diol, and modular synthesis are the key features of the successful approach.
  • Keywords
    Asymmetric synthesis , Palladium , Sulfoxide , Tetrahydrolipstatin , Frater–Seebach alkylation
  • Journal title
    Tetrahedron
  • Serial Year
    2009
  • Journal title
    Tetrahedron
  • Record number

    1100300