Title of article
Asymmetric synthesis of (−)-tetrahydrolipstatin
Author/Authors
Sadagopan Raghavan، نويسنده , , Kailash Rathore، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
10
From page
10083
To page
10092
Abstract
Attempts toward the asymmetric synthesis of (−)-tetrahydrolipstatin are described. A palladium catalyzed Wacker-type reaction to convert an alkene to a ketone, highly diastereoselective reduction of a β-hydroxy ketone, selective oxidation of a diol, and modular synthesis are the key features of the successful approach.
Keywords
Asymmetric synthesis , Palladium , Sulfoxide , Tetrahydrolipstatin , Frater–Seebach alkylation
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1100300
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