Title of article
Nicotinamide-independent asymmetric bioreduction of Cdouble bond; length as m-dashC-bonds via disproportionation of enones catalyzed by enoate reductases
Author/Authors
Clemens Stueckler، نويسنده , , Tamara C. Reiter، نويسنده , , Nina Baudendistel، نويسنده , , Kurt Faber، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
663
To page
667
Abstract
The asymmetric bioreduction of activated Cdouble bond; length as m-dashC-bonds catalyzed by a single flavoprotein was achieved via direct hydrogen transfer from a sacrificial 2-enone or 1,4-dione as hydrogen donor without requirement of a nicotinamide cofactor. Due to its simplicity, this system has clear advantages over conventional FAD-recycling systems.
Keywords
Enoate reductase , Disproportionation , Flavin , Cofactor recycling , Biotransformation
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100475
Link To Document