Title of article
Catalytic asymmetric synthesis of cyclic α-alkyl-amino acid derivatives by C,N-double alkylation
Author/Authors
Taichi Kano، نويسنده , , Ryu Sakamoto، نويسنده , , Haruka Mii، نويسنده , , Yong-Gang Wang، نويسنده , , Keiji Maruoka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
4900
To page
4904
Abstract
Catalytic asymmetric synthesis of various cyclic α-alkyl-amino acid derivatives having a tetrasubstituted α-carbon, such as α-alkylprolines has been accomplished by asymmetric phase-transfer C-alkylation of α-alkyl-amino acid derivatives and subsequent intramolecular N-alkylation.
Keywords
Asymmetric synthesis , Amino acid , Alkylation , Cyclization , Phase-transfer catalyst
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100978
Link To Document