Title of article
Coupling of 1-Alkyl-2-(bromomethyl)aziridines with Lithium Dialkylcuprates towards 1,2-Dialkylaziridines
Author/Authors
D’hooghe، Matthias نويسنده , , Rottiers، Mario نويسنده , , Jolie، Robrecht نويسنده , , Kimpe، Norbert De نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-930
From page
931
To page
0
Abstract
The reactivity of 1-alkyl-2-(bromomethyl)aziridines with respect to lithium dialkylcuprates (Gilman reagents) has been evaluated for the first time, pointing to the conclusion that these substrates can be applied successfully as synthetic equivalents for the aziridinylmethyl cation synthon towards, e.g. 2-ethyl-, 2-pentyl- and 2-(phenylmethyl)aziridines in good yields.
Keywords
nucleophilic substitution , 1,2-dialkylaziridines , Organometallics , 2-(bromomethyl)aziridines
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110294
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