• Title of article

    N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P–O bond

  • Author/Authors

    Zhengjun Quan، نويسنده , , Rong-Guo Ren، نويسنده , , Xiaodong Jia، نويسنده , , Yuxia Da، نويسنده , , Zhang Zhang، نويسنده , , Xicun Wang، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    6
  • From page
    2462
  • To page
    2467
  • Abstract
    N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P–O bond was investigated and a series of N3-ethoxymethylated heterocyclic compounds were synthesized. A mechanism in which diethyl phosphite acts as an efficient surrogate of ethanol was proposed and supported by several evidences.
  • Keywords
    N-Alkylation , P–O cleavage , Diethyl phosphite , N3-Substituted dihydropyrimidinones
  • Journal title
    Tetrahedron
  • Serial Year
    2011
  • Journal title
    Tetrahedron
  • Record number

    1103079