Title of article
Stereoselective synthesis of piperidinone and quinolinone systems via ring opening reactions using TiCl4/silyl reagents
Author/Authors
Sengodagounder Muthusamy، نويسنده , , Chinnakuzhanthai Gangadurai، نويسنده , , Janagiraman Krishnamurthi، نويسنده , , Eringathodi Suresh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
9
From page
4212
To page
4220
Abstract
Titanium(IV) chloride and silyl reagents mediated regio- and chemoselective ring opening reactions of oxa-bridged piperidinone ring systems were demonstrated. This methodology interestingly undergoes the stereoselective ring opening at the C–O bond of oxa-bridged piperidinone ring systems. Study of TiCl4 with hydride or non-hydride silyl reagents furnished the product with selectivity. This protocol is highly valuable to synthesize a range of stereoselective piperidinones, quinolinones ring systems.
Keywords
titanium(IV) chloride , piperidinones , Ring opening , Silyl reagents , Stereoselectivity , quinolinones
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103291
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