Title of article
Rhodium or palladium-catalyzed cascade aryl addition/intramolecular lactonization of phthalaldehydonitrile to access 3-aryl and 3-alkenyl phthalides
Author/Authors
Guanglei Lv، نويسنده , , Genping Huang، نويسنده , , Guangyou Zhang، نويسنده , , Changduo Pan، نويسنده , , Fan Chen، نويسنده , , Yun-Jiang Cheng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
4879
To page
4886
Abstract
A rhodium or palladium-catalyzed addition of boronic acids to phthalaldehydonitrile, followed by an intramolecular lactonization of cyano to access 3-substituted phthalides, is described. This procedure tolerates a series of functional groups, such as methoxy, fluoro, chloro, and vinyl groups. It is a novel procedure for the synthesis of 3-arylphthalides.
Keywords
Rhodium , Lactonization , Palladium , Phthalaldehydonitrile , phthalides
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103388
Link To Document