Title of article
Carbocyclization of d-glucose: syntheses of gabosine I and streptol
Author/Authors
Tony K.M Shing، نويسنده , , Y. Chen، نويسنده , , Wai-Lung Ng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
6001
To page
6005
Abstract
d-Glucose was differentially protected with a trans-diacetal at C-2,3, an ethoxymethyl ether at C-4, and a tert-butyldimethylsilyl ether at C-6, and then carbocyclized via a key Horner–Wadsworth–Emmons (HWE) olefination to give a versatile synthetic intermediate, enone 13, which was readily transformed into gabosine I and streptol.
Keywords
Carbohydrate , Natural products , Wittig reaction , Synthesis
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103523
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