Title of article
Cell differentiation inducers from a marine sponge Biemna sp.
Author/Authors
Reiko Ueoka، نويسنده , , Yuji Ise، نويسنده , , Shigeru Okada، نويسنده , , Shigeki Matsunaga، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
6679
To page
6681
Abstract
Two pyridoacridines closely related to the known isocystodamine were isolated from the marine sponge Biemna sp. together with isocystodamine. Their structures were determined on the basis of spectroscopic data. They induce the erythroid differentiation of human leukemia K562 cells with an ED50 value of 5 nM each.
Keywords
pyridoacridine , NMR , Isolation , Sponge , Cell differentiation
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103596
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