Title of article
Synthesis of polysubstituted 3H-pyrimidin-4-ones from cyanoacetamides under Vilsmeier conditions
Author/Authors
Zhiguo Zhang، نويسنده , , Can Xue، نويسنده , , Xiao Liu، نويسنده , , Qian Zhang، نويسنده , , Qun Liu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
7081
To page
7084
Abstract
A facile and efficient approach to a variety of 6-chloro-3,5-disubstituted 3H-pyrimidin-4-ones 2/6 from the readily available cyanoacetamides 1/5 under Vilsmeier conditions was developed, in which the Vilsmeier reagent plays multiple roles and the possible mechanism is discussed.
Keywords
Polysubstituted 3H-pyrimidin-4-ones , Vilsmeier reagent , Cyclopropanes , ring expansion
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103635
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