Title of article
Cyclohexadepsipeptides from Acremonium sp. BCC 28424
Author/Authors
Masahiko Isaka، نويسنده , , Arunrat Yangchum، نويسنده , , Malipan Sappan، نويسنده , , Rapheephat Suvannakad، نويسنده , , Prasert Srikitikulchai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
7
From page
7929
To page
7935
Abstract
Six new cyclohexadepsipeptides, beauvenniatins A–E (1–5), and beauvericin J (6), together with the known beauvericin (7) and enniatin B (8), were isolated from the fungus Acremonium sp. BCC 28424. The productions of minor derivatives 3–6, possessing an N-methyl-l-tyrosine, were enhanced by feeding l-tyrosine in the liquid fermentation medium. Antimalarial, antitubercular, and cytotoxic activities of these cyclodepsipeptides were evaluated.
Keywords
Beauvericin , Cyclodepsipeptide , Directed biosynthesis , enniatin , Acremonium
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103738
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