Title of article
Papuamides E and F, cytotoxic depsipeptides from the marine sponge Melophlus sp.
Author/Authors
Pritesh Prasad، نويسنده , , William Aalbersberg، نويسنده , , Klaus-D. Feussner، نويسنده , , Ryan M. Van Wagoner and Jon Clardy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
8529
To page
8531
Abstract
Two known papuamides C (1) and D (2) together with two new depsipeptides, papuamides E (3) and F (4), were isolated from an undescribed sponge of the genus Melophlus collected in the Solomon Islands. The planar structures of the compounds were elucidated on the basis of spectroscopic studies. Papuamides C–F (1–4) showed cytotoxicity against brine shrimp with LD50 values between 92 and 106 μg/mL.
Keywords
Cytotoxic , depsipeptide , Papuamide , Melophlus
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103814
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