Title of article
An efficient synthesis of 2H-indazoles via reductive cyclization of 2-nitrobenzylamines induced by low-valent titanium reagent
Author/Authors
Fang Sun، نويسنده , , Xian Feng، نويسنده , , Xuan Zhao، نويسنده , , Zhibin Huang، نويسنده , , Daqing Shi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
3851
To page
3855
Abstract
An efficient and improved synthesis of 2H-indazoles via reductive cyclization of 2-nitrobenzylamines induced by low-valent titanium reagent (TiCl4/Zn) is described. In this reaction triethylamine (TEA) was used to control the pH value. This method has the advantages of easily accessible starting materials, convenient manipulation, higher yield, shorter reaction time, and wider substrate scope.
Keywords
2H-Indazole , 2-Nitrobenzylamine , Reductive cyclization , Low-valent titanium reagent
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104464
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