Title of article
Palladium-catalyzed direct arylation using free NH2 substituted thiophene derivatives with inhibition of amination type reaction
Author/Authors
Fazia Derridj، نويسنده , , Karima Si Larbi، نويسنده , , Julien Roger، نويسنده , , Safia Djebbar، نويسنده , , Henri Doucet، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
9
From page
7463
To page
7471
Abstract
The palladium-catalyzed direct arylation at C2 or C5 of free NH2 substituted thiophene derivatives was found to proceed in moderate to high yields using a variety of aryl halides. The choice of potassium acetate as the base was found to be crucial to inhibit the amination reaction and to promote the direct arylation.
Keywords
Palladium , Catalysis , Thiophenes , aryl halides , C–H bond functionalization
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104884
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