Title of article
An approach to alicyclic ring-fused xanthines
Author/Authors
Kostiantyn Liubchak، نويسنده , , Andrey Tolmachev، نويسنده , , Oleksandr O. Grygorenko، نويسنده , , Kostiantyn Nazarenko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
8
From page
8564
To page
8571
Abstract
A convenient three-step approach to the synthesis of five to eight-membered alicyclic ring-fused xanthines was developed. The method included reaction of lactim or thiolactim ethers with 6-aminouracils, followed by bromination and copper-catalyzed arylation. The procedure allowed preparation of the title compounds in 21–36% overall yields.
Keywords
Imidazoles , Amidines , Copper-catalyzed arylation , Xantines , Nitrogen Heterocycles
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1105018
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