Title of article
Rotational isomerism in 2,4,6-tri-tert-butylanilides
Author/Authors
Nobutaka Ototake، نويسنده , , Isao Takahashi، نويسنده , , Shiori Tsukagoshi، نويسنده , , Tatsuki Maeda، نويسنده , , Osamu Kitagawa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
1013
To page
1016
Abstract
Z-Rotamers of several 2,4,6-tri-tert-butylanilides slowly isomerize at rt in CDCl3 to E-rotamers, yielding equilibrium mixtures of Z- and E-rotamers after standing for 1 week. The equilibrium ratios between the anilide rotamers in the solution depend strongly on the bulkiness of the acyl substituents as well as the formation of intramolecular hydrogen bond. Heating equilibrium mixtures in the solid state produced complete isomerization to the Z-rotamer.
Keywords
Anilides , rotamers , Amides , Isomerization , Hydrogen bonding
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105396
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