Title of article
Baylis–Hillman acetates in carbocyclic synthesis: a convenient protocol for synthesis of densely substituted indenes
Author/Authors
Deevi Basavaiah، نويسنده , , Bhavanam Sekhara Reddy، نويسنده , , Harathi Lingam، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
10
From page
1994
To page
2003
Abstract
A simple and facile strategy for synthesis of densely substituted indenes have been developed from Baylis–Hillman acetates in a two step protocol, that is, (1) via treatment with DABCO and then reaction with alkyl 3-oxobutanoates in the presence of K2CO3 (2) followed by the intramolecular Friedel–Crafts cyclization of the resulting keto-diesters using titanium tetrachloride.
Keywords
Baylis–Hillman reaction , Friedel–Crafts reaction , Chemo selectivity , Keto-diesters , Indene derivatives
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105517
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