Title of article
Evaluation of cyclopentyl methyl ether (CPME) as a solvent for radical reactions
Author/Authors
Shoji Kobayashi، نويسنده , , Hiroyuki Kuroda، نويسنده , , Yuta Ohtsuka، نويسنده , , Takashi Kashihara، نويسنده , , Araki Masuyama، نويسنده , , Kiyoshi Watanabe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
9
From page
2251
To page
2259
Abstract
We have explored the potential of cyclopentyl methyl ether (CPME) as a solvent for radical reactions. Hydrostannation, hydrosilylation, hydrothiolation, and tributyltin hydride mediated reductions were successfully carried out in CPME. GC–MS analysis indicated that CPME degraded into methyl pentanoate, cyclopentanone, 2-cyclopenten-1-ol, and cyclopentanol under thermal radical conditions, albeit only slightly. We also achieved radical-containing one-pot reactions in CPME as a demonstration of its applicability to multi-step reactions.
Keywords
Barton–McCombie radical deoxygenation , One-pot reaction , Cyclopentyl methyl ether (CPME) , radical additions , Radical reductions
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105552
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