Title of article
One-pot tandem synthesis of fluorescent 5-naphthyl-3(2H)-furanones
Author/Authors
Anastasiya G. Malʹkina، نويسنده , , Olʹga G. Volostnykh، نويسنده , , Konstantin B. Petrushenko، نويسنده , , Olesya A. Shemyakina، نويسنده , , Valentina V. Nosyreva، نويسنده , , Igorʹ A. Ushakov، نويسنده , , Boris A. Trofimov، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
7
From page
3714
To page
3720
Abstract
Fluorescent 3(2H)-furanones, 4-cyano-2,2-dialkyl-5-(1- or 2-)naphthyl-3(2H)-furanones, have been synthesized in 69–81% yield by a one-pot procedure, via the tandem reaction of tertiary cyanopropargylic alcohols with 1- and 2-naphthoic acids under mild transition-metal free conditions (Et3N, 20–25 °C for 48–192 h or 55–60 °C for 7–13 h, MeCN). The synthesized compounds fluoresce in the visible region (λmax=419–431 nm), thus being prospective fluorescent biolabels.
Keywords
Cyanopropargylic alcohols , Naphthoic acids , 3(2H)-furanones , Tandem reaction , fluorescence
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105721
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