Title of article
PIDA-promoted intramolecular transannular aziridination to synthesize bridged azatricyclic amines related to methyllycaconitine
Author/Authors
Zhi-Gang Liu، نويسنده , , Hang Cheng، نويسنده , , Meng-Jia Ge، نويسنده , , Liang Xu، نويسنده , , Feng-Peng Wang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
7
From page
5431
To page
5437
Abstract
A synthetic strategy for the modeling construction of the A/E/F ring system of lycoctonine-type C19-diterpenoid alkaloids bearing a featuring oxygen functional group at C-7 has been successfully developed. The key steps involved a diastereoselective gold(I)-catalyzed annulation to form cis-fused cyclopentene and a PIDA-promoted intramolecular transannular aziridination followed by regioselective ring cleavage to give the azatricyclic amine.
Keywords
Methyllycaconitine , C19-Diterpenoid alkaloids , A/E/F ring system , Intramolecular transannular aziridination , PIDA
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105924
Link To Document