Title of article
Enantiospecific total synthesis of indole alkaloids (+)-eburnamonine, (−)-aspidospermidine and (−)-quebrachamine
Author/Authors
John Eugene Nidhiry، نويسنده , , Kavirayani R. Prasad، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
12
From page
5525
To page
5536
Abstract
An enantiospecific total synthesis of indole alkaloids eburnamonine, aspidospermidine and quebrachamine is described from lactic acid. Synthesis of all three alkaloids is accomplished from a single chiral building block. Johnson–Claisen rearrangement of a chiral allyl alcohol is the main feature for the installation of the required quaternary centre.
Keywords
Indole alkaloids , Total synthesis , Enantiospecific synthesis , Claisen rearrangement
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105937
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