Title of article
Reactivity of PNA Thioesters in Chemical Ligation Reactions
Author/Authors
Overhand، Mark نويسنده , , Petersen، Lene نويسنده , , Koning، Martijn C. de نويسنده , , Marel، Gijsbert A. van der نويسنده , , Knaap، Matthijs van der نويسنده , , Elst، Hans van den نويسنده , , Filippov، Dmitri V. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-594
From page
595
To page
0
Abstract
The ligation rate and efficiency of PNA thioesters in the reaction with the pentapeptide CRYNK has been determined and proved to be substantially lower in comparison with the corresponding C-terminal glycine thioester.
Keywords
thioesters , native chemical ligation , peptide nucleic acid , convergent synthesis , reactivity
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110607
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