A Comparative Study of the Influence of Protecting Groups on the Reactivity of chiro-Inositol Glycosyl Acceptors

The influence of protecting groups on the reactivity of glycosyl acceptors has been investigated through a series of competitive glycosylation experiments using differently substituted C2 symmetric d-chiro-inositol derivatives. It has been shown that, for a given glycosyl donor, the protective group pattern effectively modulates the reactivity of these derivatives in the glycosylation reaction.