Title of article
Enhancement of the sliding velocity of actin filaments in the presence of ATP analogue: AMP-PNP Original Research Article
Author/Authors
Junʹichi Sakamaki، نويسنده , , Hajime Honda، نويسنده , , Eiʹichi Imai، نويسنده , , Kuniyuki Hatori، نويسنده , , Katsuhiko Shimada، نويسنده , , Koichiro Matsuno، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
8
From page
59
To page
66
Abstract
The sliding velocity of actin filaments was found to increase in the presence of ATP analogues. At 0.5 mM ATP, the presence of 2.0 mM of AMP-PNP enhanced the filament velocity from 3.2 up to 4.5 μm/s. However, 2 mM ADP decreased the velocity down to 1.1 μm/s. The results suggest that the complex conformations of myosin cross-bridges interacting with an actin filament in the presence of ATP analogues makes the entire filament move faster.
Keywords
Weakly bound state , actin , myosin , Sliding velocity , ATP analogue
Journal title
Biophysical Chemistry
Serial Year
2003
Journal title
Biophysical Chemistry
Record number
1113290
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